American Thoracic Society Conference
(Booth # 1146) in Philadelphia, PA
5/19 - 5/23
This gene is composed of 46 exons and codes for a protein in the ankyrin family. Ankyrins link integral membrane proteins to the underlying spectrin-actin cytoskeleton. Due to their function, these proteins play a key role in cell motility, activation, proliferation, contact and maintenance of specialized membrane domains. Mutations in this gene cause LongQT syndrome (LQTS) and cardiac arrhythmia.