Please be on the look out for
Ambry Representatives at :
ASCO Breast Cancer Symposium 2014
Enhancing Clinical Care Through Collaboration
San Francisco, CA
09/4/14 - 09/6/14
The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch.
Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signaling through notch 1 has also been shown to play a role in hematopoiesis.