American Thoracic Society Conference
(Booth # 1146) in Philadelphia, PA
5/19 - 5/23
The ribosomal protein L10 gene (RPL10 OMIM 312173) encodes a crucial component of the highly conserved 60S large ribosome subunit, which is required for protein synthesis. The RPL10 gene is located at Xq28 and contains 7 exons. Two missense mutations in the RPL10 gene have been in reported in affected males among two unrelated families with autism spectrum disorder (ASD) (Klauck, SM et al. Mol Psychiatry. 2006;11:1074-1084).