Systematic application of ClinGen InSiGHT APC-specific ACMG/AMP variant classification criteria alleviates the burden of variants of uncertain significance in ClinVar and LOVD databases

Alexandra Martins, Andreas Laner, Andrew Latchford, Carli Tops, Carlo Maj, Deborah Ritter, Elisabet Ognedal, Emadeldin Hassanin, Emily Nadeau, Ester Borras, Finlay A Macrae, Gabriel Capellá, Ian M Frayling, Isabel Spier, Johan de Dunnen, Karl Krahn, Khalid Mahmood, Lyman Lin, Marc S Greenblatt, Marcy E. Richardson, Margareta Nordling, Marta Pineda, Maurizio Genuardi, Sean V. Tavtigian, Sharon E. Plon, Stefan Aretz, Thomas v O Hansen, Tina Pesaran, MA, MS, CGC, Valeria Vasta, Victoria Beshay, Xiaoyu Yin, Xuemei Shi