oncology
Hereditary Cancer Testing
Industry-leading testing options to find the answers for hereditary cancer patients, designed to guide clinical action.
Why Ambry
Our approach combines a flexible, clinically driven test menu with the rigorous evidence required to make important clinical decisions with your oncology patients. By grounding our methodology in extensive published research that leads the industry, we strive to offer results that minimize ambiguity and uncertainty.
We stand behind our work with service and support, to ensure that the testing you choose yields clear, actionable insights to guide complex decisions in patient care.
Search Coverage by Genes
MOST FREQUENTLY ORDERED
Highlighted Oncology Tests
Highlighted Tests
BRCANext®
19 Genes
Guideline-based panel offering more information to identify and manage hereditary breast and/or gynecologic cancers. Optional add-ons are available for pancreatitis genes and/or limited evidence genes.
Highlighted Tests
BRCAplus®
13 Genes
Guideline-based, disease-specific test including genes associated with hereditary breast cancer, where screening and/or surgical intervention may be indicated.
Highlighted Tests
CancerNext-Expanded®
78 Genes
Comprehensive, pan-cancer test for hereditary cancer predisposition, including genes associated with a wide range of hereditary cancers such as breast, ovarian, uterine, colorectal, gastric, pancreatic, prostate, melanoma, renal, central nervous system tumors, pheochromocytoma/paraganglioma, hematologic malignancy, and other rare cancer predisposition conditions. Optional add-ons are available for pancreatitis genes and/or limited evidence genes
Highlighted Tests
ColoNext®
22 Genes
Guideline-based, disease-specific test including genes associated with hereditary colorectal and gastric cancer and polyposis. Optional add-on available for limited evidence genes.
Highlighted Tests
CustomNext-Cancer®
90 Genes
Designed for unique clinical scenarios requiring flexibility. Select from 90 genes to create a custom test for hereditary cancer predisposition
Comprehensive Testing, Customizable Testing
CancerNext-Expanded®
78 Genes
Comprehensive, pan-cancer test for hereditary cancer predisposition, including genes associated with a wide range of hereditary cancers such as breast, ovarian, uterine, colorectal, gastric, pancreatic, prostate, melanoma, renal, central nervous system tumors, pheochromocytoma/paraganglioma, hematologic malignancy, and other rare cancer predisposition conditions. Optional add-ons are available for pancreatitis genes and/or limited evidence genes
Comprehensive Testing, Customizable Testing
CancerNext®
41 Genes
Guideline-based, pan-cancer test that covers the most common hereditary cancer types, including hereditary breast, ovarian, pancreatic, prostate, colorectal/polyps, endometrial, gastric, small bowel, urothelial, and renal cancers.
Comprehensive Testing, Customizable Testing
CustomNext-Cancer®
90 Genes
Designed for unique clinical scenarios requiring flexibility. Select from 90 genes to create a custom test for hereditary cancer predisposition
For patients with a personal/family history of breast cancer, For risk assessment of multiple hereditary cancers
BRCANext®
19 Genes
Guideline-based panel offering more information to identify and manage hereditary breast and/or gynecologic cancers. Optional add-ons are available for pancreatitis genes and/or limited evidence genes.
For patients with a personal/family history of breast cancer, For risk assessment of multiple hereditary cancers
BRCAplus®
13 Genes
Guideline-based, disease-specific test including genes associated with hereditary breast cancer, where screening and/or surgical intervention may be indicated.
For patients with a personal/family history of breast cancer, For risk assessment of multiple hereditary cancers
CancerNext-Expanded®
78 Genes
Comprehensive, pan-cancer test for hereditary cancer predisposition, including genes associated with a wide range of hereditary cancers such as breast, ovarian, uterine, colorectal, gastric, pancreatic, prostate, melanoma, renal, central nervous system tumors, pheochromocytoma/paraganglioma, hematologic malignancy, and other rare cancer predisposition conditions. Optional add-ons are available for pancreatitis genes and/or limited evidence genes
For patients with a personal/family history of breast cancer, For risk assessment of multiple hereditary cancers
CancerNext®
41 Genes
Guideline-based, pan-cancer test that covers the most common hereditary cancer types, including hereditary breast, ovarian, pancreatic, prostate, colorectal/polyps, endometrial, gastric, small bowel, urothelial, and renal cancers.
For patients with a personal/family history of gastrointestinal cancer and/or polyps , For risk assessment of multiple hereditary cancers
CancerNext-Expanded®
78 Genes
Comprehensive, pan-cancer test for hereditary cancer predisposition, including genes associated with a wide range of hereditary cancers such as breast, ovarian, uterine, colorectal, gastric, pancreatic, prostate, melanoma, renal, central nervous system tumors, pheochromocytoma/paraganglioma, hematologic malignancy, and other rare cancer predisposition conditions. Optional add-ons are available for pancreatitis genes and/or limited evidence genes
For patients with a personal/family history of gastrointestinal cancer and/or polyps , For risk assessment of multiple hereditary cancers
CancerNext®
41 Genes
Guideline-based, pan-cancer test that covers the most common hereditary cancer types, including hereditary breast, ovarian, pancreatic, prostate, colorectal/polyps, endometrial, gastric, small bowel, urothelial, and renal cancers.
For patients with a personal/family history of gastrointestinal cancer and/or polyps , For risk assessment of multiple hereditary cancers
ColoNext®
22 Genes
Guideline-based, disease-specific test including genes associated with hereditary colorectal and gastric cancer and polyposis. Optional add-on available for limited evidence genes.
Single gene or single syndrome testing options
APC seq and del/dup
1 Gene
Includes testing of the APC gene which is associated with an increased risk for colorectal polyps and cancer
Single gene or single syndrome testing options
Ataxia-telangiectasia (AT)
1 Gene
Ataxia-telangiectasia (AT)
Single gene or single syndrome testing options
BMPR1A & SMAD4 seq and del/dup
2 Genes
Juvenile polyposis syndrome (JPS)
Single gene or single syndrome testing options
BRCA1/BRCA2
2 Genes
Germline mutations are implicated in up to 50% of hereditary breast cancer cases
Single gene or single syndrome testing options
Hereditary leiomyomatosis and renal cell carcinoma
1 Gene
Hereditary leiomyomatosis and renal cell carcinoma (HLRCC)
Single gene or single syndrome testing options
Li-Fraumeni syndrome
1 Gene
Li-Fraumeni syndrome
Single gene or single syndrome testing options
MSH2 seq & del/dup & EPCAM del/dup
2 Genes
Single gene or single syndrome testing options
Multiple endocrine neoplasia type 1
1 Gene
Multiple endocrine neoplasia type I (MEN1)
Single gene or single syndrome testing options
Multiple endocrine neoplasia type 2 and familial medullary thyroid cancer
1 Gene
Multiple endocrine neoplasia type 2 (MEN2) and familial medullary thyroid cancer (FMTC)
Single gene or single syndrome testing options
MUTYH seq and del/dup
1 Gene
Includes testing of the MUTYH gene which is associated with an increased risk for colorectal polyps and cancer
Single gene or single syndrome testing options
Neurofibromatosis 2 (NF2)
1 Gene
Neurofibromatosis 2 (NF2)
Single gene or single syndrome testing options
Nevoid basal cell carcinoma (Gorlin syndrome)
1 Gene
Nevoid basal cell carcinoma (Gorlin syndrome)
Single gene or single syndrome testing options
NF1 seq and del/dup
1 Gene
Neurofibromatosis 1 (NF1)
Single gene or single syndrome testing options
Schwannomatosis
1 Gene
Schwannomatosis
Single gene or single syndrome testing options
STK11 seq and del/dup
1 Gene
Peutz-Jeghers syndrome
Single gene or single syndrome testing options
Tuberous sclerosis complex (TSC)
2 Genes
Tuberous sclerosis complex (TSC)
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