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How to Handle a Variant of Uncertain Significance (VUS)

Thursday, March 20, 2025
4:00am PDT
1 hour
C.E.U.: 1 Category 1 Contact Hour
P.A.C.E.: 1 Unit

This webinar will cover the basics of genetic testing and how results are interpreted, with a focus on variants of uncertain significance (VUS). We will review was VUSs are, why they occur, and their impact on clinical management. Attendees will learn how to identify key information in genetic reports, understand current management recommendations for VUSs, and explore available resources for clinicians.  We will also cover steps to take when there are concerns about a VUS. Finally, we will examine the history and future of variant interpretation highlighting advancements in research, population databases, functional studies, and emerging technologies.

Level of Instruction: Basic

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Caitlin Reid
Oncology Genomic Science Liaison
Caitlin Reid, CGC, is a certified Genetic Counselor and Genomic Science Liaison at Ambry Genetics. She serves as a clinical liaison for the field team to educate health care providers and key opinion leaders on genetic testing and genomic medicine. Caitlin previously worked as an Oncology Genetic Counselor at the University of Iowa in the […]

Caitlin joined Ambry Genetics in 2021 as the Oncology Genomic Science Liaison for the Midwest territory. In her current role, she serves as a clinical liaison for the field team to educate health care providers and key opinion leaders on genetic testing and genomic medicine. Caitlin previously worked as an Oncology Genetic Counselor at the University of Iowa in the Holden Comprehensive Cancer center. Caitlin received her Bachelor of Science degree in Biology with a concentration in cell and developmental biology from the University of Iowa. She earned her Master of Science degree in Genetic Counseling from the University of Michigan in 2018 and is certified by the American Board of Genetic Counseling.