Collaborator: Baylor Charles A. Sammons Cancer Center

• Results of next-generation sequencing panels in a large community-based hereditary cancer risk program

  April 2, 2026

• The Clinical Utility of Next Generation Sequencing Results in a Community-Based Hereditary Cancer Risk Program

• Patient and genetic counselor perceptions of in-person versus telephone genetic counseling for hereditary breast/ovarian cancer

• Splicing profile by capture RNA-seq identifies pathogenic germline variants in tumor suppressor genes

  Abstract Germline variants in tumor suppressor genes (TSGs) can result in RNA mis-splicing and predisposition to cancer. However, identification of variants that impact splicing remains a challenge, contributing to a substantial proportion of patients with suspected hereditary cancer syndromes remaining without a molecular diagnosis. To address this, we used capture RNA-sequencing (RNA-seq) to generate a…

• Creating an open-source gene curation database from the Gene Curation Coalition (GenCC)

  April 2, 2026