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NEWS

Science, Stories & the Future of Genomics

For clinicians, patients, and the curious — insights on genomics, hereditary conditions, and the stories that remind us why this work matters.

Articles Tagged: VUS

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January 20, 2026

The Gene Scene: APOB

In this Gene Scene, Haley Streff, MS, CGC, covers the APOB gene and its association with familial hypercholesterolemia.
Gene Scene
Genetic Counselors
Genetic Testing
VUS
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September 2, 2025

The Gene Scene: RPS20

The Gene Scene covers RPS20
Gene Scene
Genetic Testing
VUS
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November 15, 2024

How the Ambry Patient for Life™ Program Minimizes the Need for Provider-Initiated Exome Reanalysis Requests

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Melissa Holman, Genomic Science Liaison
One of the unique benefits of exome testing is the ability to return to the data from the initial analysis and reevaluate it for new,…
Genetic Testing
Genetic Testing Accuracy
Multigene Panel Testing
Tag
VUS
Whole Exome Sequencing
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October 31, 2024

Striking the Perfect Balance in Designing Hereditary Cancer Tests: The Ambry Approach

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Jessica Grzybowski, Lead Genetic Counselor, Reporting – RNA, Ambry Genetics
Ambry’s balanced approach to designing hereditary cancer tests ensures our panels remain relevant and impactful, helping clinicians manage hereditary cancer risk with confidence.
Genetic Testing
Genetic Testing Accuracy
Hereditary Cancer
Multigene Panel Testing
Variant of Unknown Significance
VUS
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October 17, 2024

The Evolution of Hereditary Cancer Testing: Why Pan-Cancer Panels Are the Future of Genetic Risk Assessment

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Elizabeth Chao, Laboratory Director, Ambry Genetics
Pan-cancer panels offer more comprehensive diagnoses, personalized risk assessments, and targeted prevention and treatment strategies.
BRCA1 & 2
Genetic Testing
Genetic Testing Accuracy
Hereditary Cancer
Multigene Panel Testing
Ovarian Cancer
Variant of Unknown Significance
VUS
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July 31, 2024

The Importance of TCLR in Mismatch Repair Variant Classification: A Genetic Counselor’s Perspective

Alyssa Valentine, MS, CGC, shares insights into a patient case where the incorporation of TCLR resulted in a major impact on MMR gene variant classification.
Gene Mutation
Genetic Testing
Genetic Testing Accuracy
VUS