Gene-Specific Cancer Associations and Sensitivity of Genetic Testing Criteria

Wednesday, January 15, 2020

2:00am PST

1 hour

C.E.U.: 1 Category 1 Contact Hour

P.A.C.E.: 1 Unit

The content of this webinar is primarily based on a recent publication involving a large laboratory-based multigene panel cohort. First, gene-specific cancer risk associations will be presented, which were derived from comparing multigene panel testing cases to reference controls from gnomAD. Next, the attendee will be navigated through the prevalence of pathogenic variants among different clinical testing indications. Finally, the sensitivity of BRCA1/2 and Lynch syndrome testing criteria will be explored, with a focus on opportunities to improve upon identification of individuals with cancer-predisposing germline variants.

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Holly Laduca

Sr. Manager, Clinical Affairs Research, Ambry Genetics

Ms. LaDuca is a board-certified genetic counselor. In her current role as Sr. Manager of Clinical Affairs Research at Ambry Genetics, Ms. LaDuca oversees clinical research efforts, focusing on the translational application of Ambry’s research. She also oversees clinical data management and data sharing efforts. Her research interests include clinical implementation of polygenic risk scores and improving access to risk assessment and genetic testing. Ms. LaDuca received her M.S. in Genetic Counseling from Northwestern University and practiced clinically as a cancer genetic counselor prior to joining Ambry eight years ago.

Sarah Campian

Genetic Specialist, Ambry Genetics

Sarah Campian joined Ambry Genetics in 2018 after four years as a clinical cancer genetic counselor at the Grosfeld Cancer Genetics Center at Beaumont Health in Royal Oak, Michigan. She is a Senior Genomic Science Liaison, supporting Ambry’s oncology and reproductive health product lines. In her role, Sarah provides clinical support and education to healthcare […]

Sarah Campian joined Ambry Genetics in 2018 as the Oncology Genetic Specialist for the Great Lakes territory. She previously worked as a clinical genetic counselor at the Grosfeld Cancer Genetics Center at Beaumont Health. Her research interests include Lynch syndrome and identification of gene mutation carriers in minority populations. Sarah received her Bachelors of Science degree in Biology from Saginaw Valley State University. She earned her Masters of Science degree in Genetic Counseling from Wayne State University and is certified by the American Board of Genetic Counseling.