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Automation for Agilent Microarray-Based Comparative Genomic Hybridization (aCGH) Assays: A CostEffective Approach to Increased Sample Throughput and Reliability

Session:
#1097
Date:
Tuesday, Feb 6, 2018 10:00am – 12:00pm
Conference:
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Authors:
Aarani Arulmoli, Aaron Campbell, Christian Chua, Emily Greene, Fernando Valdez, Jacqueline Caesar-Bennett, Jose Gonzalez, Joy Crandall, Navanjot Batth
  • Implementation of automation allows for increased sample integrity, permits run-time data capture and allows for sample tracking capabilities to provide real time processing status through LIMS integration.
  •  Manual vs. automated sample processing show run to run consistency and comparable quality control data, such as DLRS and signal to noise ratio.
  • Combined application of automation and assay miniaturization result in increased per run sample throughput, as well as, a total decreased assay cost of 55% with respect to manual aCGH processing.
Abstract