Cancer risks are elevated among relatives of MRE11A, RAD50 and NBN mutation carriers but similar to mutation negative families in a laboratory based cohort
Genes for which cancer risks are not well characterized are included on clinical nextgeneration sequencingbased multigene panel tests (MGPT), including MRE11A, RAD50, and NBN (MRN).
Authors: Dajun Qian; Shuwei Li; Virginia Speare; Holly LaDuca; Hsiao-Mei Lu