The Gene Scene covers MSH2 and associated Lynch syndrome diagnoses.

The Gene Scene covers CDKN2A. Pathogenic variants can cause melanoma-pancreatic cancer syndrome.

The Gene Scene covers LDLR and its effect on hypercholesterolemia

Melissa Frey—a gynecologic oncologist, cancer geneticist, and researcher—discusses the critical importance of early cancer risk assessment and Ambry’s Progeny program.

Combining annual breast density monitoring with a validated, evolving risk model like Tyrer-Cuzick offers the most accurate roadmap for personalized screening and early detection.

This installment of The Gene Scene covers the FBN1 gene (NM_000138.4). Pathogenic variants in this gene are known to cause Marfan syndrome and other conditions.